Mayo Clinic and University of California-San Francisco researchers believe they have found a typo in the human genetic code that causes one type of brain tumors.
The researchers found what they believe triggers gliomas using ?genome-wide association studies,? Mayo pathologist Dr. Robert Jenkins said in an interview.
Such ?GWAS? studies in the past decade have identified regions of the human genome that likely play a role in particular diseases like diabetes, heart disease or gliomas.
The ultimate goal of GWAS is to find the genetic alteration that actually causes the disease.
But,??they have not been very successful,? Jenkins said.
?What?s really exciting about our study is we?ve been able to do that,? he said.
Seven possible genetic variations were reviewed after previous research showed part of human chromosome-number-8 might be associated with brain tumors.
Researchers found a single alteration in a protein base-pair of the human genetic code (DNA), which confers a relative risk for gliomas, Mayo announced.
Article source: http://postbulletin.com/news/stories/display.php?id=1506431
Source: http://cancerkick.com/2012/08/28/mayo-clinic-makes-exciting-discovery-in-brain-cancer-research/
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